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My Cart> Cell Biology > Cell Detection > Cell Growth Factor > Recombinant Human BTLA/B-andT-lymphocyte attenuator/CD272(Fc fusion)Purity：≥95% as determined by reducing SDS-PAGE.
Storage：Powder:＜-20℃ for long store;RT，3 weeks.Liquid:4-7℃，2-7 days;＜-20℃，3 months.
Appearance：Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
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| Appearance | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| Purity | ≥95% as determined by reducing SDS-PAGE. |
| Storage | Powder:＜-20℃ for long store;RT，3 weeks.Liquid:4-7℃，2-7 days;＜-20℃，3 months. |
| Transport Condition | The product is shipped at ambient temperature. |
| Background | B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain.BTLA expression is induced during activation of T cells，and BTLA remains expressed on Th1 cells but not Th2 cells.Like PD1 and CTLA4，BTLA interacts with a B7 homolog，B7H4.However，unlike PD-1 and CTLA-4，BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R)，not just the B7 family of cell surface receptors.BTLA is a lymphocyte inhibitory receptor that inhibits lymphocytes during immune response.BTLA also is a ligand for tumor necrosis factor (receptor) superfamily，member 14 (TNFRSF14)，also known as herpes virus entry mediator (HVEM).BTLA-HVEM complexes negatively regulate T-cell immune responses. |
| Source | Human cells |
| Solvent | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Endotoxin | Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test. |
| Unit | Piece |
| Specification | 10ug 50ug 500ug 1mg |
Recombinant Human B- and T-Lymphocyte Attenuator is produced by our Mammalian expression system and the target gene encoding Lys31-Leu150 is expressed with a Fc tag at the C-terminus.
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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