EPO mimetic peptide-1
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Cat.No：CLP1734 Solarbio
CAS：186526-28-3
Purity：≥95%
Appearance：Lyophilized powder
Storage：Store at -20℃，2 years.(Avoid freeze/thaw cycles)
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PI3K/Akt/mTOR
Endocrinology & Hormones
Protein Tyrosine Kinase/PTK
Angiogenesis
HIF
Immunology & Inflammation
Stem Cells
Apoptosis
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ER Stress
Cell Cycle
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Ubiquitin
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Pipette & Dispenser & Pipette Dispensing Instrument
Oscillating Mixing & Stirring & Dispersing Instrument
Temperature Control & Sampling & Grinding Crushing Instrument
Sterilization & Filtration Instruments
PCR Instrument & Light Glue Instrument
Spectrophotometer
Centrifuge
Shaker
Vacuum Pump
Other Small Instruments
Product Information
| Product Type | Peptides |
| CAS | 186526-28-3 |
| Sequence(1LC) | GGTYSCHFGPLTWVCKPQGG |
| Sequence(3LC) | Gly-Gly-Thr-Tyr-Ser-Cys-His-Phe-Gly-Pro-Leu-Thr-Trp-Val-Cys-Lys-Pro-Gln-Gly-Gly |
| Molecular Formula | C94H135N25O26S2 |
| Molecular Weight | 2095.36 |
| Purity | ≥95% |
| Appearance | Lyophilized powder |
| Salt Form | Trifluoroacetate salt |
| Source | Synthetic |
| Storage | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| Category/Label | Other Peptides |
| Background | EPO mimetic peptide-1 (EMP-1)， a 20 amino acid peptide. EPO mimetic peptide-1 stimulates cell proliferation， affects cell cycle and induces the production of reticulocytes in vivo. |
| In Vitro | EPO mimetic peptide-1 shows inhibition of tracer 125I-labeled EPO binding with an IC50 value of 0.2 μM. EPO mimetic peptide-1 (0-50 mM; 48 h) stimulates proliferation of both TF-1 and B6Sut cells in a dose-dependent manner. EPO mimetic peptide-1 (1 and 10 μM) promots erythroid colony formation from human peripheral blood and murine bone marrow. EPO mimetic peptide-1 (10 μM; 10 min) induces the phosphorylation of proteins. EPO mimetic peptide-1 (1 and 10 μM; 0-18 h) affects cell cycle. |
| In Vivo | EPO mimetic peptide-1 (1 and 2 mg; once) induces the production of reticulocytes over the background of endogenous in normal， untreated mice containing endogenous basal levels of EPO mice. |
| Reference | [1]. Wrighton NC， et al. Small peptides as potent mimetics of the protein hormone erythropoietin. Science. 1996 Jul 26;273(5274):458-64. |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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