Prepro-TRH-(160-169)
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Cat.No：CLP1586 Solarbio
CAS：122018-91-1
Purity：≥95%
Appearance：Lyophilized powder
Storage：Store at -20℃，2 years.(Avoid freeze/thaw cycles)
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PI3K/Akt/mTOR
Endocrinology & Hormones
Protein Tyrosine Kinase/PTK
Angiogenesis
HIF
Immunology & Inflammation
Stem Cells
Apoptosis
Metabolic Enzyme & Protease
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ER Stress
Cell Cycle
Cytoskeleton
DNA Damage & DNA Repai
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Ubiquitin
JAK/STAT
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Pipette & Dispenser & Pipette Dispensing Instrument
Oscillating Mixing & Stirring & Dispersing Instrument
Temperature Control & Sampling & Grinding Crushing Instrument
Sterilization & Filtration Instruments
PCR Instrument & Light Glue Instrument
Spectrophotometer
Centrifuge
Shaker
Vacuum Pump
Other Small Instruments
Product Information
| Product Type | Peptides |
| CAS | 122018-91-1 |
| Sequence(1LC) | SFPWMESDVT |
| Sequence(3LC) | Ser-Phe-Pro-Trp-Met-Glu-Ser-Asp-Val-Thr |
| Molecular Formula | C54H75N11O18S1 |
| Molecular Weight | 1198.3 |
| Purity | ≥95% |
| Appearance | Lyophilized powder |
| Salt Form | Trifluoroacetate salt |
| Source | Synthetic |
| Storage | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| Category/Label | Hormone and Related Peptides |
| Background | Prepro-TRH-(160-169) is one of the connecting peptides of thyrotropin-releasing hormone prohormone (pro-TRH)， potentiates TRH-induced thyrotropin (TSH) release. |
| In Vitro | In primary cultures of rat anterior pituitary cells， Prepro-TRH-(160-169) (Ps4) is able to increase intracellular Ca2+ concentration ([Ca2+]i) rapidly， in 15 s. |
| In Vivo | In urethane-anesthetized rats， Prepro-TRH-(160-169) (Ps4; 100 ng， 150 ng and 200 ng; injected into dorsal motor nucleus (DMN)) potentiates TRH in the DMN-evoked gastric acid secretion through an action that is peptide and site specific. |
| Reference | [1]. H Yang， et al. Prepro-TRH-(160-169) potentiates gastric acid secretion stimulated by TRH microinjected into the dorsal motor nucleus of the vagus. Neurosci Lett. 1994 Jun 6;174(1):43-6. [2]. J P Roussel， et al. Somatostatin blocks the potentiation of TRH-induced TSH secretion from perifused pituitary fragments and the change in intracellular calcium concentrations from dispersed pituitary cells elicited by prepro-TRH (PS4) or by tri-iodothyronine. J Mol Endocrinol. 1997 Aug;19(1):87-97. |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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