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My Cart> Peptides > Hormone and Related Peptides > Delta (Phospho) Sleep Inducing PeptideCAS：70754-23-3
Purity：≥95%
Appearance：Lyophilized powder
Storage：Store at -20℃，2 years.(Avoid freeze/thaw cycles)
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| Product Type | Peptides |
| CAS | 70754-23-3 |
| Sequence(1LC) | WAGGDA-pS-GE |
| Sequence(3LC) | Trp-Ala-Gly-Gly-Asp-Ala-pSer-Gly-Glu |
| Molecular Formula | C35H49N10O18P1 |
| Molecular Weight | 928.79 |
| Purity | ≥95% |
| Appearance | Lyophilized powder |
| Salt Form | Trifluoroacetate salt |
| Source | Synthetic |
| Storage | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| Category/Label | Hormone and Related Peptides |
| Background | Delta (Phospho) Sleep Inducing Peptide (DSIP-P) is a long-lasting sleep-promoting peptide. Delta (Phospho) Sleep Inducing Peptide induces changes in the circadian locomotor behavior in rats. |
| In Vitro | Delta (Phospho) Sleep Inducing Peptide (20-300 nM) increases rat pineal N-acetyltransferase (NAT) activity induced by norepinephrine in vitro. |
| In Vivo | Delta (Phospho) Sleep Inducing Peptide (0.1 nmol/kg; i.v.; once daily for 4 times) induces changes in the circadian locomotor behavior. Delta (Phospho) Sleep Inducing Peptide (20 or 200 pmol/kg; inject into the 3rd cerebroventricle of male rats immediately before the onset of the dark period) increases slow-wave sleep and paradoxical sleep during the subsequent dark period without shortening sleep latency at a dose of 200 pmol/kg. |
| Reference | [1]. Graf M， et al. Effects of repeated DSIP and DSIP-P administration on the circadian locomotor activity of rats. Pharmacol Biochem Behav. 1981 Nov;15(5):717-21. [2]. Nakagaki K， et al. Sleep-promoting effect following intracerebroventricular injection of a phosphorylated analogue of delta sleep-inducing peptide (DSIP-P) in rats. Neurosci Lett. 1988 Aug 31;91(2):160-4. [3]. Graf MV， Schoenenberger GA. Delta sleep-inducing peptide modulates the stimulation of rat pineal N-acetyltransferase activity by involving the alpha 1-adrenergic receptor. J Neurochem. 1987 Apr;48(4):1252-7. |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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