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Woodtide

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Cat.No：CLP1475 Solarbio

CAS：634592-23-7

Purity：≥95%

Appearance：Lyophilized powder

Storage：Store at -20℃，2 years.(Avoid freeze/thaw cycles)

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Product Information

Product Type	Peptides
CAS	634592-23-7
Sequence(1LC)	KKISGRLSPIMTEQ
Sequence(3LC)	Lys-Lys-Ile-Ser-Gly-Arg-Leu-Ser-Pro-Ile-Met-Thr-Glu-Gln
Molecular Formula	C68H122N20O21S1
Molecular Weight	1587.88
Purity	≥95%
Appearance	Lyophilized powder
Salt Form	Trifluoroacetate salt
Source	Synthetic
Storage	Store at -20℃，2 years.(Avoid freeze/thaw cycles)
Category/Label	Substrate and Enzyme Inhibitors
Background	Woodtide is a substrate for the DYRK (DYRK) family of kinases whose sequence is based on that around the DYRK phosphorylation site in FKHR.
In Vitro	Immunoprecipitated FLAG-dDYRK2 or FLAG-MNB is assayed using 50 μM Woodtide or 50 μM activation-loop peptide with two additional lysines attached to the N terminus to allow it to bind to P81 paper (KKSSCYVDRKIYTYIQSRFY for dDYRK2 or KKSSCQLGQRIYHYIQSRFY for MNB). Both kinases efficiently phosphorylated the synthetic exogenous substrate peptide Woodtide， but neither dDYRK2 nor MNB phosphorylated their activation-loop peptide.
Reference	[1]. Pamela A Lochhead， et al. Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs. Cell. 2005 Jun 17;121(6):925-36. [2]. Linda E Campbell， et al. Differing substrate specificities of members of the DYRK family of arginine-directed protein kinases. FEBS Lett. 2002 Jan 2;510(1-2):31-6.
Unit	Bottle
Specification	1mg 5mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.

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