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My CartCAS：106128-98-7
Purity：≥95%
Appearance：Lyophilized powder
Storage：Store at -20℃，2 years.(Avoid freeze/thaw cycles)
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| Product Type | Peptides |
| CAS | 106128-98-7 |
| Sequence(1LC) | Ac-ASQKRPSQRHG |
| Sequence(3LC) | Ac-Ala-Ser-Gln-Lys-Arg-Pro-Ser-Gln-Arg-His-Gly |
| Molecular Formula | C52H88N22O17 |
| Molecular Weight | 1293.39 |
| Purity | ≥95% |
| Appearance | Lyophilized powder |
| Salt Form | Trifluoroacetate salt |
| Source | Synthetic |
| Storage | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| Category/Label | Substrate and Enzyme Inhibitors |
| Background | Myelin Basic Protein (1-11) is an encephalitogenic epitope of myelin basic protein (MBP). Myelin Basic Protein (1-11) can be used for induction of experimental autoimmune encephalomyelitis (EAE). |
| In Vitro | Myelin Basic Protein (1-11) (0-10 μg/mL) stimulates IL-2 production in MBP-TCR CD4 T cells. |
| In Vivo | Myelin Basic Protein (1-11) (100 μg/mL)-pulsed DC cells (i.p.) leads to experimental autoimmune encephalomyelitis (EAE) when transferred into irradiated B10.PL mice. Myelin Basic Protein (1-11) (100 μg， i.p.) induced tolerance to MBP in adult mice and prevents MBP-induced EAE. |
| Reference | [1]. Dittel BN， et al. Presentation of the self antigen myelin basic protein by dendritic cells leads to experimental autoimmune encephalomyelitis. J Immunol. 1999 Jul 1;163(1):32-9. [2]. Gaur A， et al. Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide-induced anergy. Science. 1992 Nov 27;258(5087):1491-4. |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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