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My Cart> Peptides > Substrate and Enzyme Inhibitors > [Ala1，3，11，15]-Endothelin (53-63)CAS：121204-87-3
Purity：≥95%
Appearance：Lyophilized powder
Storage：Store at -20℃，2 years.(Avoid freeze/thaw cycles)
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| Product Type | Peptides |
| CAS | 121204-87-3 |
| Sequence(1LC) | ASASSLMDKEAVYFAHLDIIW |
| Sequence(3LC) | Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp |
| Molecular Formula | C109H163N25O32S1 |
| Molecular Weight | 2367.67 |
| Purity | ≥95% |
| Appearance | Lyophilized powder |
| Salt Form | Trifluoroacetate salt |
| Source | Synthetic |
| Storage | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| Category/Label | Substrate and Enzyme Inhibitors |
| Background | [Ala1，3，11，15]-Endothelin (53-63) is an ETB agonist. [Ala1，3，11，15]-Endothelin (53-63) has selectivity for ETB with IC50 values range from 0.33 nM to 0.61 nM. [Ala1，3，11，15]-Endothelin (53-63) can be used for the research of vasoconstriction |
| In Vitro | [Ala1，3，11，15]-Endothelin (53-63) (0.1 μM) has selectivity for ETB with IC50 values of 0.61 nM， 0.61 nM， 0.33 nM， 2200 nM in Bronchus， Lung， Cerebellum and VSMC， respectively. |
| Reference | [1]. Nakamichi K， et al. Different distribution of endothelin receptor subtypes in pulmonary tissues revealed by the novel selective ligands BQ-123 and [Ala1，3，11，15]ET-1. Biochem Biophys Res Commun. 1992 Jan 15;182(1):144-50. |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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