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My Cart> Cell Biology > Cell Detection > Cell Growth Factor > Recombinant Human uPAR/CD87Purity：≥95% as determined by reducing SDS-PAGE.
Storage：Lyophilized protein should be stored at ≤ -20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20℃ for 3 months.
Appearance：Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
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| Appearance | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| Purity | ≥95% as determined by reducing SDS-PAGE. |
| Storage | Lyophilized protein should be stored at ≤ -20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20℃ for 3 months. |
| Transport Condition | The product is shipped at ambient temperature. |
| Background | The Urokinase Type Plasminogen Activator (uPA) receptor (uPAR) is a widely expressed receptor for urokinase plasminogen activator (uPA) and pro-uPA.uPAR / CD87 is a highly glycosylated，55-60kDa integral membrane protein linked to the plasma membrane by a glycosylphosphatidylinositol (GPI) anchor.uPAR is expressed by T-cells，NK cells，monocytes，and neutrophils as well as non-hematopoietic cells that include vascular endothelial cells，fibroblasts，smooth muscle cells，keratinocytes，placental trophoblasts，hepatocytes，and a wide variety of tumor cells (including breast，colon，and prostate carcinoma，melanoma).It plays a critical role in the regulation of cell-surface plasminogen activation in physiological and pathological conditions，and it is also involved in cellular adhesion，the transmission of extracellular signals across the plasma membrane and the subsequent regulation of gene expression.uPAR has been implicated in several biological processes including angiogenesis，monocyte migration，cancer metastasis，trophoblast implantation，and wound healing.Human uPAR is encoded as a 313 amino acid residue polypeptide，excluding a 22 residue signal peptide and shows 60-70% similarity with the murine uPAR amino acid sequence although binding of uPA to uPAR shows strong species specificity. |
| Source | Human cells |
| Solvent | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Endotoxin | Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test. |
| Unit | Piece |
| Specification | 10ug 50ug 500ug 1mg |
Recombinant Human Urokinase Plasminogen Activator Surface Receptor is produced by our Mammalian expression system and the target gene encoding Leu23-Arg303 is expressed with a 6His tag at the C-terminus.
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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