Anti-SPNS1 Polyclonal Antibody
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Cat.No：K115011P Solarbio
Reactivity：Rat,Mouse,Human
Application： IHC
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Host：Rabbit
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Secondary Antibodies
SAlexa Fluor-Conjugated
Other Fluorescent-Conjugated
Other-Conjugated
Colloidal Gold Reagent
Alkaline Phosphatase(AP)-Conjugated
Colloidal Gold-Conjugated
FITC-Conjugated
Biotin-Conjugated
Purified Secondary Antibodies
Allophycocyanin(APC)-Conjugated
CY Fluorescent-Conjugated
Phycoglobin(PE)-Conjugated
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Inhibitors & Antagonists & Agonists
PI3K/Akt/mTOR
Endocrinology & Hormones
Protein Tyrosine Kinase/PTK
Angiogenesis
HIF
Immunology & Inflammation
Stem Cells
Apoptosis
Metabolic Enzyme & Protease
Autophagy
ER Stress
Cell Cycle
Cytoskeleton
DNA Damage & DNA Repai
Epigenetics
Ubiquitin
JAK/STAT
GPCR & G Protein
Neuronal Signal Pathway
MAPK
NF-κB
Membrane Transporter & Ion Channel
TGF-β/Smad
Hippo
Antibody-drug Conjugate/ADC Related
Others
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Instruments
Pipette & Dispenser & Pipette Dispensing Instrument
Oscillating Mixing & Stirring & Dispersing Instrument
Temperature Control & Sampling & Grinding Crushing Instrument
Sterilization & Filtration Instruments
PCR Instrument & Light Glue Instrument
Spectrophotometer
Centrifuge
Shaker
Vacuum Pump
Other Small Instruments
Product Information
Experimental Images
Related Products
Related Conjugation
Related Paper
Technical Q&A
Product Information
| Name | Anti-SPNS1 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Predicted Reactivity | Cow |
| Dilution Ratio | IHC 1:50-200. |
| Target | SPNS1 |
| Background | Plays a critical role in the phospholipid salvage pathway from lysosomes to the cytosol (PubMed:36161949).Mediates the rate-limiting，proton-dependent，lysosomal efflux of lysophospholipids，which can then be reacylated by acyltransferases in the endoplasmic reticulum to form phospholipids (PubMed:36161949).Selective for zwitterionic headgroups such as lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE)，can also transport lysophosphatidylglycerol (LPG)，but not other anionic lysophospholipids，sphingosine，nor sphingomyelin (PubMed:36161949).Transports lysophospholipids with saturated，monounsaturated，and polyunsaturated fatty acids，such as 1-hexadecanoyl-sn-glycero-3-phosphocholine，1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine and 1-(4Z，7Z，10Z，13Z，16Z，19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine，respectively (PubMed:36161949).Can also transport lysoplasmalogen (LPC with a fatty alcohol) such as 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine (PubMed:36161949).Essential player in lysosomal homeostasis (PubMed:36161949).May be involved in necrotic or autophagic cell death (PubMed:12815463). |
| Swiss Prot | Q9H2V7 |
| Gene ID | 83985 |
| Subcellular Location | Cytoplasm |
| Immunogen | A synthetic peptide of human SPNS1 |
| Public Immunogen Range | 330-380/528aa |
| Calculated MW | 25/49/51/57kDa |
| Observed MW | 50kDa |
| Purification Method | Octanoic acid-ammonium sulfate precipitation |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Piece | bottle |
| Specification | 50ul 100ul |
| Reactivity | Human Mouse Rat |
| Application | IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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