Anti-OAZ1 Polyclonal Antibody
Cat.No:K114807P Solarbio
Reactivity:Mouse,Human,Rat
Application: IHC
Storage:Store at -20℃. Avoid freeze / thaw cycles.
Host:Rabbit
Qty:
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My CartReactivity:Mouse,Human,Rat
Application: IHC
Storage:Store at -20℃. Avoid freeze / thaw cycles.
Host:Rabbit
Qty:
Size:
Name | Anti-OAZ1 Polyclonal Antibody |
Host | Rabbit |
Clone Type | Polyclonal Antibody |
Subtype | IgG |
Predicted Reactivity | Cow;Xenopus laevis;Chicken;Hamster;Zebrafish |
Dilution Ratio | IHC 1:50-200. |
Target | OAZ1 |
Background | The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family; which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting; which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC); the key enzyme in polyamine biosynthesis; thus; completing the auto-regulatory circuit. This gene encodes antizyme 1; the first member of the antizyme family; that has broad tissue distribution; and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation; as well as inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs; and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization. Alternatively spliced transcript variants have also been noted for this gene. |
Swiss Prot | P54368 |
Gene ID | 4946 |
Subcellular Location | Cytoplasm |
Immunogen | A synthetic peptide of human OAZ1 |
Public Immunogen Range | 50-100/228aa |
Calculated MW | 25kDa |
Purification Method | Affinity purification |
Storage Buffer | PBS with 50% Glycerol, 0.03% Proclin300, 0.5% BSA, pH 7.3. |
Storage | Store at -20℃. Avoid freeze / thaw cycles. |
Unit | 支 |
Specification | 50ul 100ul |
Reactivity | Human Mouse Rat |
Application | IHC |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder:Quick spin before use. If you have any questions, please contact us.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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