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Anti-CD45 Monoclonal Antibody

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Cat.No：K011290M Solarbio

Reactivity：Human

Application： FCM

Storage：Store at 4℃ in dark.Do not freeze.

Host：Mouse

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Product Information

Name	Anti-CD45 Monoclonal Antibody
Host	Mouse
Clone Type	Monoclonal Antibody
Subtype	IgG2a
Target	CD45
Background	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth，differentiation，mitotic cycle，and oncogenic transformation. This PTP contains an extracellular domain，a single transmembrane segment and two tandem intracytoplasmic catalytic domains，and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes，or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases，and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene，which encode distinct isoforms，have been reported. [provided by RefSeq，Jul 2008].
Swiss Prot	P08575
Gene ID	5788
Subcellular Location	Cell membrane
Storage	Store at 4℃ in dark.Do not freeze.
Piece	Piece
Specification	100ug 1mg
Reactivity	Human
Application	FCM

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Kindly reminder：Quick spin before use. If you have any questions, please contact us.

Note：

1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.