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Anti-CD40 Monoclonal Antibody

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Cat.No：K011285M Solarbio

Reactivity：Human

Application： FCM

Storage：Store at 4℃ in dark.Do not freeze.

Host：Mouse

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Product Information

Name	Anti-CD40 Monoclonal Antibody
Host	Mouse
Clone Type	Monoclonal Antibody
Subtype	IgG2b
Target	CD40
Background	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching，memory B cell development，and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand，which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation，and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq，Jul2008].
Swiss Prot	P25942
Gene ID	958
Subcellular Location	Cell membrane
Storage	Store at 4℃ in dark.Do not freeze.
Unit	Piece
Specification	100ug 1mg
Reactivity	Human
Application	FCM

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Kindly reminder：Quick spin before use. If you have any questions, please contact us.

Note：

1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.