Anti-CD23(PerCP-Cy5.5) Monoclonal Antibody
Cat.No:K011228M Solarbio
Reactivity:Human
Application: FCM
Storage:Store at 4℃ in dark.Do not freeze.
Host:Mouse
Qty:
Size:
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My CartReactivity:Human
Application: FCM
Storage:Store at 4℃ in dark.Do not freeze.
Host:Mouse
Qty:
Size:
Name | Anti-CD23(PerCP-Cy5.5) Monoclonal Antibody |
Host | Mouse |
Clone Type | Monoclonal Antibody |
Subtype | IgG1,κ |
Dilution Ratio | FCM 5uL/Test. |
Target | CD23 |
Background | The CD23 antigen is the low affinity IgE Fc receptor,which is a 49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature,conventional B cells (but not on peritoneal CD5+ B cells),and can also be found on the surface of T cells,macrophages,platelets and EBV transformed B lymphoblasts. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic Lymphocytic leukemia. CD23 is expressed by B cells in the follicular mantle but not by proliferating germinal centre cells. CD23 is also expressed by eosinophils. CD23 is distinct from the high affinity IgE receptors found on basophils and mast cells,which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface expression appears to be integral with the complex IgE system,which involves interactions of cells,cytokines,antibodies and regulatory factors. CD23 has been described as a “membrane bound cytokine,' in that the soluble cleavage products of CD23 are themselves able to act as cytokines in vitro. |
Swiss Prot | P06734 |
Gene ID | 2208 |
Subcellular Location | Cell membrane |
Storage | Store at 4℃ in dark.Do not freeze. |
Unit | Piece |
Specification | 25T 100T |
Reactivity | Human |
Application | FCM |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder:Quick spin before use. If you have any questions, please contact us.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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