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Anti-CD279(PE) Monoclonal Antibody

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Cat.No：K011155M Solarbio

Reactivity：Human

Application： FCM

Storage：Store at 4℃ in dark.Do not freeze.

Host：Mouse

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Product Information

Name	Anti-CD279(PE) Monoclonal Antibody
Host	Mouse
Clone Type	Monoclonal Antibody
Subtype	IgG1，κ
Dilution Ratio	FCM 5uL/Test.
Target	CD279
Background	This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice，expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. CD279 is an immunoglobulin superfamily member，also known as Programmed Cell Death 1. Programmed Cell Death 1 is expressed on a subset of CD4-CD8 thymocytes，and on activated T and B cells. Programmed Cell Death 1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The Programmed Cell Death 1 ligands，PDL1 (also known as B7H1) and PDL2 (B7DC)，are members of the B7 immunoglobulin superfamily.
Swiss Prot	Q15116
Gene ID	5133
Subcellular Location	Cell membrane
Storage	Store at 4℃ in dark.Do not freeze.
Piece	Piece
Specification	25T 100T
Reactivity	Human
Application	FCM

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Kindly reminder：Quick spin before use. If you have any questions, please contact us.

Note：

1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.