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Anti-CD5(APC-Cy7) Monoclonal Antibody

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Cat.No：K010986M Solarbio

Reactivity：Human

Application： FCM

Storage：Store at 4℃ in dark.Do not freeze.

Host：Mouse

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Product Information

Name	Anti-CD5(APC-Cy7) Monoclonal Antibody
Host	Mouse
Clone Type	Monoclonal Antibody
Subtype	IgG1，κ
Dilution Ratio	FCM 5uL/Test.
Target	CD5
Background	CD5 is a 55kDa T lymphocyte single chain transmembrane glycoprotein. It is present on all mature T lymphocytes，on most thymocytes and on many T cell leukemias and lymphomas. It reacts with a subpopulation of activated B cells. CD5/Lyt1 antigen is a monomeric type I transmembrane glycoprotein expressed on thymocytes，T lymphocytes，and a subset of B lymphocytes，but not on natural killer (NK) cells. It has been identified as the major ligand of the B cell antigen CD72. The frequency of CD5+ B cells exhibits strain dependent variation，and the phenotypic，anatomical，functional，developmental，and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage，known as B1 cells. Binding of CD5 on the T cell surface can augment alloantigen or mitogen induced lymphocyte proliferation and induces increased cytosolic free calcium，IL2 secretion，and IL2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T cell and B cell receptors.
Swiss Prot	P06127
Gene ID	921
Subcellular Location	Cell membrane
Storage	Store at 4℃ in dark.Do not freeze.
Piece	Piece
Specification	25T 100T
Reactivity	Human
Application	FCM

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Kindly reminder：Quick spin before use. If you have any questions, please contact us.

Note：

1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.