Mutated EGFR-IN-1
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Cat.No：IM6620 Solarbio
CAS：1421372-66-8
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
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Inhibitors & Antagonists & Agonists
PI3K/Akt/mTOR
Endocrinology & Hormones
Protein Tyrosine Kinase/PTK
Angiogenesis
HIF
Immunology & Inflammation
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Apoptosis
Metabolic Enzyme & Protease
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Cytoskeleton
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Ubiquitin
JAK/STAT
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Inhibitors & Antagonists & Agonists
PI3K/Akt/mTOR
Endocrinology & Hormones
Protein Tyrosine Kinase/PTK
Angiogenesis
HIF
Immunology & Inflammation
Stem Cells
Apoptosis
Metabolic Enzyme & Protease
Autophagy
ER Stress
Cell Cycle
Cytoskeleton
DNA Damage & DNA Repai
Epigenetics
Ubiquitin
JAK/STAT
GPCR & G Protein
Neuronal Signal Pathway
MAPK
NF-κB
Membrane Transporter & Ion Channel
TGF-β/Smad
Hippo
Antibody-drug Conjugate/ADC Related
Others
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Instruments
Pipette & Dispenser & Pipette Dispensing Instrument
Oscillating Mixing & Stirring & Dispersing Instrument
Temperature Control & Sampling & Grinding Crushing Instrument
Sterilization & Filtration Instruments
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Spectrophotometer
Centrifuge
Shaker
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> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Angiogenesis > Mutated EGFR-IN-1
Product Information
| CAS | 1421372-66-8 |
| Name | Mutated EGFR-IN-1 |
| Molecular Formula | C25H31N7O |
| Molecular Weight | 445.56 |
| Solubility | Soluble in DMSO ≥7mg/mL |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)N)N(C)CCN(C)C)OC |
| InChIKey | HTNTZPBKKCORTP-UHFFFAOYSA-N |
| InChI | InChI=1S/C25H31N7O/c1-30(2)12-13-31(3)23-15-24(33-5)21(14-19(23)26)29-25-27-11-10-20(28-25)18-16-32(4)22-9-7-6-8-17(18)22/h6-11，14-16H，12-13，26H2，1-5H3，(H，27，28，29) |
| PubChem CID | 78358313 |
| Target Point | EGFR |
| Passage | Angiogenesis;Protein Tyrosine Kinase/RTK |
| Background | Mutated EGFRin-1 is an intermediate inhibitor of mutant EGFR (L858R EGFR, Exonl9 deletion-activated mutation and T790M resistance mutation). |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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