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My CartCAS：39537-23-0
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 39537-23-0 |
| Name | L-Alanyl-L-glutamine |
| Molecular Formula | C8H15N3O4 |
| Molecular Weight | 217.22 |
| Solubility | Soluble in Water ≥5mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 475-290-9 |
| MDL | MFCD00133046 |
| SMILES | CC(C(=O)NC(CCC(=O)N)C(=O)O)N |
| InChIKey | HJCMDXDYPOUFDY-WHFBIAKZSA-N |
| InChI | InChI=1S/C8H15N3O4/c1-4(9)7(13)11-5(8(14)15)2-3-6(10)12/h4-5H，2-3，9H2，1H3，(H2，10，12)(H，11，13)(H，14，15)/t4-，5-/m0/s1 |
| PubChem CID | 123935 |
| Target Point | Others |
| Passage | Others |
| Background | L-Alanyl-L-glutamine is a dipeptide, which has a variety of important biological activities, and is also a substitute additive for L-glutamine, with good solubility and stability. |
| Unit | Bottle |
| Specification | 20mg 100mg |
Examples of using this product（for reference only）
In Vivo：
Mice（early weaning mice；2% L-alanyl-L-glutamine；7d）：
To investigate the effects of Gln supplementation on early weaning mice, early weaning pups from the same litter were randomly divided into two groups on the basis of similar body weights (n = 3–4 per group). Mice in the weaned group were free to drink water, while the Ala-Gln group was free to drink 2% L-alanyl-L-glutamine (Solarbio, Beijing, China) supplemented water, equaling a solution of 111 mM Ala-Gln. To assess the effects of alanine (Solarbio) supplementation on early weaning mice, early weaning pups from the same litter were randomly divided into two groups on the basis of similar body weights (n = 3–4 per group). The weaned group was free to drink water, while the Ala group was free to drink a solution of 111 mM of L-alanine (Solarbio) in water. Three or more weaning mice were caged together in each group. We measured the body weight every day and recorded food consumption weekly in the groups. The water was changed every 3 days. On day 7 post-weaning, the mice were sacrificed to collect jejunual tissues and blood for further analysis.
Reference：
Tian J, Li Y, Bao X, Yang F, Tang X, Jiang Q, Yang C, Yin Y, Yao K. Glutamine boosts intestinal stem cell-mediated small intestinal epithelial development during early weaning: Involvement of WNT signaling. Stem Cell Reports. 2023 Jul 11;18(7):1451-1467. doi: 10.1016/j.stemcr.2023.05.012. Epub 2023 Jun 15. PMID: 37327782.
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Tian J, et al. Stem Cell Reports. 2023 Jul 11;18(7):1451-1467.
Tian J, et al. Stem Cell Reports. 2023 Jul 11;18(7):1451-1467.
Tian J, et al. Stem Cell Reports. 2023 Jul 11;18(7):1451-1467.
Tian J, et al. Stem Cell Reports. 2023 Jul 11;18(7):1451-1467.
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