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My CartCAS：78842-13-4
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 78842-13-4 |
| Name | 2'-Deoxy-2'-fluoroguanosine |
| Molecular Formula | C10H12FN5O4 |
| Molecular Weight | 285.23 |
| Solubility | Soluble in DMSO ≥5mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00923832 |
| SMILES | C1=NC2=C(N1C3C(C(C(O3)CO)O)F)N=C(NC2=O)N |
| InChIKey | UXUZARPLRQRNNX-DXTOWSMRSA-N |
| InChI | InChI=1S/C10H12FN5O4/c11-4-6(18)3(1-17)20-9(4)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4，6，9，17-18H，1H2，(H3，12，14，15，19)/t3-，4-，6-，9-/m1/s1 |
| PubChem CID | 135415565 |
| Target Point | Influenza Virus |
| Passage | Anti-infection |
| Background | 2 -Deoxy-2 -fluoroguanosine， a nucleoside analogue， is an effective inhibitor of influenza virus. |
| Biological Activity | 2′-Deoxy-2′-fluoroguanosine， a nucleoside analog， is a potent inhibitor of influenza virus strains， with an EC90 of <0.35 μM for influenza virus A and B strains. 2′-Deoxy-2′-fluoroguanosine significantly inhibits replication of influenza virus in the upper respiratory tract， resulting in amelioration of fever and nasal inflammation[1][2]. |
| IC50 | EC90: <0.35 μM (influenza virus A and B)[1] |
| Data Literature Source | [1]. Tisdale M，et，al. Inhibition of influenza virus transcription by 2'-deoxy-2'-fluoroguanosine. Antimicrob Agents Chemother. 1995 Nov;39(11):2454-8. [2]. Jakeman KJ，et，al. Efficacy of 2'-deoxy-2'-fluororibosides against influenza A and B viruses in ferrets. Antimicrob Agents Chemother. 1994 Aug;38(8):1864-7. |
| Unit | Bottle |
| Specification | 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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