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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > PI3K/Akt/mTOR > NSC 781406CAS：1676893-24-5
Molecular Formula：C29H27F2N5O5S2
Molecular Weight：627.68
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
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| CAS | 1676893-24-5 |
| Name | NSC 781406 |
| Molecular Formula | C29H27F2N5O5S2 |
| Molecular Weight | 627.68 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C#CCN4CCN(CC4)S(=O)(=O)C)NS(=O)(=O)C5=C(C=C(C=C5)F)F |
| InChIKey | BBRINJUWZRLWKK-UHFFFAOYSA-N |
| InChI | InChI=1S/C29H27F2N5O5S2/c1-41-29-27(34-43(39，40)28-8-6-23(30)18-25(28)31)17-22(19-33-29)21-5-7-26-24(16-21)20(9-10-32-26)4-3-11-35-12-14-36(15-13-35)42(2，37)38/h5-10，16-19，34H，11-15H2，1-2H3 |
| PubChem CID | 127025628 |
| Target Point | PI3K;mTOR |
| Passage | PI3K/Akt/mTOR |
| Background | NSC781406 is a highly effective PI3K and mTOR inhibitor. |
| Biological Activity | NSC781406 is a highly potent PI3K and mTOR inhibitor with an IC50 of 2 nM for PI3Kα.[1] |
| Data Literature Source | [1]. Chen Y， et al. Discovery of benzenesulfonamide derivatives as potent PI3K/mTOR dual inhibitors with in vivo efficacies against hepatocellular carcinoma. Bioorg Med Chem. 2016 Mar 1;24(5):957-66. |
| Unit | Bottle |
| Specification | 1mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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