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My CartCAS：233254-24-5
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 233254-24-5 |
| Name | Tomeglovir |
| Molecular Formula | C23H27N3O4S |
| Molecular Weight | 441.54 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | CC(C)(CO)C(=O)NC1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC3=C2C=CC=C3N(C)C |
| InChIKey | OSQAKHSYTKBSPB-UHFFFAOYSA-N |
| InChI | InChI=1S/C23H27N3O4S/c1-23(2，15-27)22(28)24-16-11-13-17(14-12-16)25-31(29，30)21-10-6-7-18-19(21)8-5-9-20(18)26(3)4/h5-14，25，27H，15H2，1-4H3，(H，24，28) |
| PubChem CID | 475330 |
| Target Point | CMV |
| Passage | Anti-infection |
| Background | Tomeglovir is an anti-CMV compound that inhibits the progression of viral DNA polyconjugations. |
| Biological Activity | Tomeglovir 是一种CMV 病毒抑制剂，可抑制病毒 DNA 多联体的进程，对 HCMV 和 MCMV 的 IC50 值分别为 0.34 μM 和 0.039 μM。[1] |
| IC50 | HCMV: 0.34μM(IC50);mCMV: 0.039μM(IC50) [1] |
| In Vitro | Tomeglovir has potent inhibitors of the human cytomegalovirus(HCMV)and murine cytomegalovirus(MCMV)in vitro.[1] |
| In Vivo | In the immunodeficient mice，tomeglovir(≥10mg/kg)demonstrated anti-HCMV activity in vivo.[1] |
| Data Literature Source | [1]. Weber O，et al. Inhibition of murine cytomegalovirus and human cytomegalovirus by a novel non-nucleosidic compound in vivo. Antiviral Res. 2001 Mar;49(3):179-89. [2]. Reefschlaeger J，et al. Novel non-nucleoside inhibitors of cytomegaloviruses (BAY 38-4766): in vitro and in vivo antiviral activity and mechanism of action. J Antimicrob Chemother. 2001 Dec;48(6):757-67. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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