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My CartCAS：1404-90-6
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 1404-90-6 |
| Name | Vancomycin |
| Molecular Formula | C66H75Cl2N9O24 |
| Molecular Weight | 1449.25 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 215-772-6 |
| MDL | MFCD05664587 |
| SMILES | C[C@H]1[C@H]([C@@](C[C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)[C@H]([C@H](C(=O)N[C@H](C(=O)N[C@H]5C(=O)N[C@@H]7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9O)O)[C@H](NC(=O)[C@H]([C@@H](C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)CC(=O)N)NC(=O)[C@@H](CC(C)C)NC)O)Cl)CO)O)O)(C)N)O |
| InChIKey | MYPYJXKWCTUITO-LYRMYLQWSA-N |
| InChI | InChI=1S/C66H75Cl2N9O24/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4，70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92/h6-11，13-19，23-24，34-35，42，44，46-54，56-57，65，71，78-81，83-87H，12，20-22，70H2，1-5H3，(H2，69，82)(H，72，92)(H，73，89)(H，74，91)(H，75，93)(H，76，88)(H，77，90)(H，94，95)/t24-，34+，35-，42+，44-，46+，47+，48-，49+，50-，51+，52+，53+，54-，56+，57+，65-，66-/m0/s1 |
| PubChem CID | 14969 |
| Target Point | Bacterial |
| Passage | Anti-infection |
| Background | Vancomycin is an antibiotic commonly used to treat various bacterial infections. |
| Biological Activity | Vancomycin 是一种治疗细菌感染的抗生素。[1-2] |
| In Vitro | 万古霉素会改变细胞膜的通透性，并选择性地抑制核糖核酸的合成。万古霉素对大量革兰氏阳性细菌具有活性，对大多数金黄色葡萄球菌菌株具有拮抗作用。[1] |
| In Vivo | 万古霉素能在急性期改善艰难梭菌感染小鼠的临床评分和组织病理学，但治疗后效果不佳。减少万古霉素的暴露可减少复发并提高CDI的存活率。[2] |
| Data Literature Source | [1]. Watanakunakorn C. Mode of action and in-vitro activity of vancomycin. J Antimicrob Chemother. 1984 Dec;14 Suppl D:7-18. [2]. Warren CA，et al. Vancomycin treatment's association with delayed intestinal tissue injury，clostridial overgrowth，and recurrence of Clostridium difficile infection in mice. Antimicrob Agents Chemother. 2013 Feb;57(2):689-96. |
| Unit | Bottle |
| Specification | 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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