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My CartCAS：54-42-2
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 54-42-2 |
| Name | Idoxuridine |
| Molecular Formula | C9H11IN2O5 |
| Molecular Weight | 354.1 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-207-8 |
| MDL | MFCD00134656 |
| SMILES | C1C(C(OC1N2C=C(C(=O)NC2=O)I)CO)O |
| InChIKey | XQFRJNBWHJMXHO-RRKCRQDMSA-N |
| InChI | InChI=1S/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2，5-7，13-14H，1，3H2，(H，11，15，16)/t5-，6+，7+/m0/s1 |
| PubChem CID | 5905 |
| Target Point | Antiviral |
| Passage | Anti-infection |
| Background | It is an iodized thymidine analogue that inhibits viral activity by inhibiting DNA polymerase, which affects viral replication. |
| Biological Activity | Idoxuridine 可通过抑制 DNA 聚合酶和影响病毒复制来抑制病毒活性，尤其是病毒性眼部感染，包括单纯疱疹性角膜炎。伊多呋啶对猫疱疹病毒的 IC50 值为 4.3 μM。[1] |
| IC50 | Feline herpesvirus type-1(FHV-1): 4.3μM(IC50)[1] |
| In Vitro | 碘苷(2-10 μM，72 小时)的 IC50 值为 4.3 μM 的抗病毒药物。[1] |
| Data Literature Source | [1]. Maggs DJ，et al. In vitro efficacy of ganciclovir，cidofovir，penciclovir，foscarnet，idoxuridine，and acyclovir against feline herpesvirus type-1. Am J Vet Res. 2004 Apr;65(4):399-403. |
| Unit | Bottle |
| Specification | 250mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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