Lipopolysaccharide (LPS) Extraction Kit

Lipopolysaccharide (LPS) is the main component of the outer membrane of the cell wall of Gram-negative bacteria, which has a complex structure and high thermal stability (it is completely inactivated after dry heat sterilization at 250℃ for 2h). Due to the historical reasons for the discovery of LPS, the concept of LPS is now almost equivalent to endotoxin. LPS is composed of polysaccharide chain and lipid A, and the polysaccharide chain of different bacteria is highly variable, which determines the serotype of bacteria. Lipid A mainly affects the toxicity of LPS. LPS can induce a cascade of immune stimulation and toxic pathophysiological activities in the body, including the release of endotoxins that cause septic shock leading to peripheral vascular collapse. Meningitis is often diagnosed clinically by detecting the presence of LPS. Due to the close relationship between LPS and the body's immune function, life science research often extracts LPS for related research, such as clarifying the structure, metabolism, immunology, physiology, toxicity, and biosynthetic pathways of LPS. Induces the synthesis and secretion of growth promoting factors such as interleukin; Induced disease studies in animal models such as inflammatory responses, acute lung injury. LPS extraction kit can quickly extract bacterial lipopolysaccharides in simple steps, with high extraction yield, time saving, and low protein and nucleic acid contamination.

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Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Note：

1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.