Anti-GLRB Polyclonal Antibody - SAlexa Fluor 350
Cat: K108984P - SAlexa Fluor 350
Summary:
| 【Product name】：Anti-GLRB Polyclonal Antibody - SAlexa Fluor 350 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2743 | 【Swiss Prot】：P48167 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human GLRB | |
| 【Public Immunogen Range】：85-135/497aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents.
Verified picture: