Anti-FRS2 Polyclonal Antibody
Cat: K108939P
Summary:
| 【Product name】：Anti-FRS2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10818 | 【Swiss Prot】：Q8WU20 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of Human FRS2 | |
| 【Public Immunogen Range】：1-51/508aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
Verified picture:
Western blot analysis with FRS2 antibody diluted at 1:2000;Lane: HUVEC,Vero.
Immunohistochemistry of paraffin-embedded Human lung cancer with FRS2 antibody diluted at 1:100.