Anti-SARS spike glycoprotein S1 Polyclonal Antibody - SAlexa Fluor 750
Cat: K009372P - SAlexa Fluor 750
Summary:
| 【Product name】：Anti-SARS spike glycoprotein S1 Polyclonal Antibody - SAlexa Fluor 750 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Swiss Prot】：P59594 | |
| 【Tested applications】：ELISA,IF,ICC,IHC | |
| 【Recommended dilution】：ELISA 1:5000-10000. IHC 1:100-500. ICC 1:100-500. IF 1:100-500. | |
| 【Immunogen】：A synthetic peptide of human SARS glycoprotein S1 | |
| 【Public Immunogen Range】：101-200/1255aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
S1 attaches the virion to the cell membrane by interacting with human ACE2 and CLEC4M/DC-SIGNR, initiating the infection. Binding to the receptor and internalization of the virus into the endosomes of the host cell probably induces conformational changes in the S glycoprotein. Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.
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