Anti-SARS spike glycoprotein S1 Polyclonal Antibody - RBITC
Cat: K009372P - RBITC
Summary:
| 【Product name】：Anti-SARS spike glycoprotein S1 Polyclonal Antibody - RBITC | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Swiss Prot】：P59594 | |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human SARS glycoprotein S1 | |
| 【Public Immunogen Range】：101-200/1255aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
S1 attaches the virion to the cell membrane by interacting with human ACE2 and CLEC4M/DC-SIGNR, initiating the infection. Binding to the receptor and internalization of the virus into the endosomes of the host cell probably induces conformational changes in the S glycoprotein. Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.
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