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Anti-COL22A1 Polyclonal Antibody - SAlexa Fluor 680
Cat: K116545P - SAlexa Fluor 680
Summary:
【Product name】:Anti-COL22A1 Polyclonal Antibody - SAlexa Fluor 680 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:169044 【Swiss Prot】:Q8NFW1
【Observed】:140kDa
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:500-2000. IHC 1:100-300.
【Immunogen】:A synthetic peptide of human COL22A1
【Public Immunogen Range】:1150-1200/1626aa
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene encodes member of the collagen family which is thought to contribute to the stabilization of myotendinous junctions and strengthen skeletal muscle attachments during contractile activity. It belongs to the fibril-associated collagens with interrupted triple helix (FACIT) subset of the collagen superfamily, which associate with collagen fibers through their C-terminal collagenous domains and mediate protein-protein interactions through their N-terminal noncollagenous domains. The encoded protein is deposited in the basement membrane zone of the myotendinous junction which is present only at the tissue junctions of muscles, tendons, the heart, articular cartilage, and skin. A knockdown of the orthologous zebrafish gene induces a muscular dystrophy by disruption of the myotendinous junction.
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