Anti-PDCD1 Polyclonal Antibody - SAlexa Fluor 660
Cat: K116507P - SAlexa Fluor 660
Summary:
| 【Product name】：Anti-PDCD1 Polyclonal Antibody - SAlexa Fluor 660 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：5133 | 【Swiss Prot】：Q15116 |
| 【Observed】：50kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of human PDCD1 | |
| 【Public Immunogen Range】：180-230/288aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions， including those of effector CD8+ T cells. In addition， this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas， and has demonstrated to play a role in anti-tumor immunity. Moreover， this protein has been shown to be involved in safeguarding against autoimmunity， however， it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.
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