Anti-ERLIN1 Polyclonal Antibody - HRP
Cat: K116467P - HRP
Summary:
| 【Product name】：Anti-ERLIN1 Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10613 | 【Swiss Prot】：O75477 |
| 【Observed】：42kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：Recombinant protein of human ERLIN1 | |
| 【Public Immunogen Range】：47-346aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1，4，5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway， which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62.
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