Anti-WRAP73 Polyclonal Antibody - SAlexa Fluor 350
Cat: K116443P - SAlexa Fluor 350
Summary:
| 【Product name】：Anti-WRAP73 Polyclonal Antibody - SAlexa Fluor 350 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：49856 | 【Swiss Prot】：Q9P2S5 |
| 【Observed】：47kDa | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human WRAP73 | |
| 【Public Immunogen Range】：261-420aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome. Required for the centrosomal localization of SSX2IP and normal mitotic bipolar spindle morphology (PubMed:26545777). Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1， SSX2IP， CEP290 and PIBF1/CEP90. Required for ciliogenesis and involved in the removal of the CEP97:CCP110 complex from the mother centriole. Involved in ciliary vesicle formation at the mother centriole and required for the docking of vesicles to the basal body during ciliogenesis; may promote docking of RAB8A- and ARL13B-containing vesicles (PubMed:26675238).
Verified picture: