Anti-PRAMEF6 Polyclonal Antibody - SAlexa Fluor 640
Cat: K116432P - SAlexa Fluor 640
Summary:
| 【Product name】：Anti-PRAMEF6 Polyclonal Antibody - SAlexa Fluor 640 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：440561 | 【Swiss Prot】：Q5VXH4 |
| 【Observed】：58kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：Recombinant protein of human PRAMEF6 | |
| 【Public Immunogen Range】：80-430aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex， which mediates ubiquitination of target proteins， leading to their degradation (PubMed:26138980). The CRL2(PRAMEF6) complex mediates ubiquitination and degradation of truncated MSRB1/SEPX1 selenoproteins produced by failed UGA/Sec decoding (PubMed:26138980).
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