Anti-CHRNA3 Polyclonal Antibody
Cat: K115481P
Summary:
| 【Product name】：Anti-CHRNA3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1136 | 【Swiss Prot】：P32297 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:25-100. | |
| 【Immunogen】：Recombinant protein of human CHRNA3 | |
| 【Public Immunogen Range】：1-240aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit，as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.
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